TIER2 (enhancing Trust, Integrity and Efficiency in Research through next-level Reproducibility) will increase reproducibility of scientific research results that will bring trust, integrity, and efficiency to the European Research Area (ERA) and the global Research and Innovation (R&I) system. The project will boost knowledge on reproducibility, create tools, engage communities, implement interventions and policy across different contexts to increase re-use and overall quality of research results. TIER2 aims to build an evidence-base on the extent and efficacy of existing reproducibility practices and co-create new tools to enhance reproducibility across diverse contexts.